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姓名 赵利霞 性别:
职称 研究员 学历 博士
电话 010-62849338 传真: 010-62849685
Email: zlx@rcees.ac.cn 邮编: 100085
地址 北京市海淀区双清路18号
简历:

赵利霞,研究员, 博士生导师。2005年毕业于中国科学院生态环境研究中心获得理学博士学位,同年进入该中心环境化学与生态毒理学国家重点实验室工作。主要从事环境污染物纳米发光分析及其降解转化过程中高毒性中间体的动态追踪研究。以提高灵敏度和特异性为目标,研究环境污染物快速、高通量发光分析新方法和反应新机制;以化学发光分析方法为基础,研究环境污染物光催化降解转化过程中自由基、高毒性中间产物等关键中间体的动态跟踪及其生物效应,为揭示污染物降解转化机制及其毒性风险的快速评价提供新技术和新仪器。曾获Nanoscience Awards 2015年度奖,中国科学院院长优秀奖。承担国家自然科学基金、中科院仪器研制项目等多项国家课题。已在Environ. Sci. Technol., Anal. Chem., Trends Anal. Chem., Nanoscale 等SCI收录期刊上发表论文70余篇;申请/授权专利9项;出版/参与专著4部;研制仪器1 台。

 

研究方向:

活性氧介导的污染物转化分析及毒性风险

招生方向:
环境分析化学、环境科学。欢迎分析化学,物理化学,环境科学等专业学生报考。
专家类别:
高级
职务:
社会任职:

现任中国分析测试协会标记免疫分析专业委员会常委。

承担科研项目情况:

(1)国家自然科学面上基金:氯酚光催化降解毒性中间产物生成阻断动态研究及其机制探讨(21876184);负责
(2)国家自然科学面上基金:基于化学发光的卤代酚降解动态机制研究及其毒性风险评价(21677152);负责
(3)国家自然科学面上基金:纳米粒子增强单线态氧通道均相化学发光免疫研究及其在环境雌激素类物质中的应用(21177138);负责
(4)国家自然科学青年基金:纳米粒子催化降解环境有机氯代物的化学发光行为及其机制研究(20907060);负责
(5)国家自然科学基金面上项目:分子印迹磁性纳米材料的制备及其在环境中的应用(20575073); 负责
(6)中科院仪器装备项目:环境雌激素检测用化学发光免疫分析仪研究(YZ0632); 负责
(7)国家重点基础研究发展计划(973计划)课题2之子课题:化学发光对TiO2光催化降解卤代物过程中界面活性氧研究(2010CB933502);负责
(8)国家重大科研仪器研制项目:高通量多功能成组毒理学分析系统(21527901);参与
(9)国家重点基础研究发展计划(973计划)课题1:水处理功能纳米材料的制备、修饰及其界面过程(2011CB936001);参与

获奖及荣誉:
 
代表论著:

1.Hai-Yan Ma, Lixia Zhao,* Da-Bin Wang, Hui Zhang, Liang-Hong Guo*, Dynamic Tracking of Highly Toxic Intermediates in Photocatalytic Degradation of Pentachlorophenol by Chemiluminescence,Environ. Sci. Technol. 2018, 52, 2870?2877.
2.Dabin Wang, Lixia Zhao*, Dan Wang,Li Yan, Chuanyong Jing, Hui Zhang, Liang-Hong Guo* and Ning Tang, Direct evidence for surface long-lived superoxide radicals on photo-generated in TiO2 and other metal oxide suspensions, Phys. Chem. Chem. Phys, 2018, 20, 18978-18985.
3.Hongyun Niu, Yang Zheng, Saihua Wang, Lixia Zhao, Shipeng Yang, Yaqi Cai, Contimuous generation of hydroxyl radicals for highly efficient elimination of chlorophenols and phenols catalyzed by heterogeneous fenton-like catalysts yolk/shell Pd@Fe3O4@metal organic frameworks, Journal of Hazardous materials, 2018, 346, 174-183.
4.Dan Wang, Lixia Zhao*, Haiyan Ma, Hui Zhang, Liang-Hong Guo*, quantitative analysis of reactive oxygen species photogenerated on metal oxide nanoparticles and their bacteria toxicity: the role of superoxide radicals, Environ. Sci. Technol. 2017, 51 (17), 10137–10145
5.Lixia Zhao*, Dan Wang, Gen Shi, Ling Lin*, Dual-labeled chemiluminescence enzyme immunoassay for simultaneous measurement of total prostate specific antigen(TPSA) and free prostate specific antigen (FPSA), luminescence, 2017, 32, 1547-1553
6.Wenting Song, Lixia Zhao, Zhendong Sun, Xiaoxi Yang, Qunfang Zhou*, Guibin Jiang, A novel high throughput screening assay for binding affinities of perfleoroalkyl iodide for estrogen receptor alpha and beta isoforms, Talanta, 2017, 175, 413-420
7.Changjiang Hou, Lixia Zhao*, Fanglan Geng, Dan Wang, Liang-Hong Guo*, Donor/acceptor nanopartical pair-based singlet oxygen channeling homogenous chemiluminescence immunoassay for quantitative determination of bisphenol A, Anal. Bioanal. Chem., 2016, 408, 8795-8804
8.Hui Zhang, Lixia Zhao, Fanglan Geng, Liang-Hong Guo*, Bin Wan, Yu Yang, Carbon dots decorated graphitic carbon nitride as an efficient metal-free photocatalyst for phenol degradation, Applied catalysis B: Environmental, 2016, 180, 656-662.
9.Yongguang Yin, Xiaoya Yang, Ligang Hu, Zhiqiang Tan, Lixia Zhao, Zhen Zhang, Jingfu Liu, Guibin Jiang, Superoxide-Mediated extracellular biosynthesis of silver nanoparticles by the fungus fusarium oxysporum, Environ. Sci. Technol. Lett, 2016, 3(4) 160-165
10.Dabin Wang, Lixia Zhao*, Liang-Hong Guo*, Hui Zhang, Bin Wan, Yu Yang, Online Quantification of O2?- and H2O2 and Their Formation Kinetics in Ultraviolet (UV)-Irradiated Nano-TiO2 Suspensions by Continuous Flow Chemiluminescence, ACTA CHIMICA SINICA, 2015, 86(21), 10533-10539.
11.Lixia Zhao*, Fan Di, Hui Zhang, Bin Wan, Yu Yang, Synergistic induced chemiluminescence of carbon dots by oxidants and strong alkaline solution, Sci. Adv. Today, 2015,1,25216
12.Dabin Wang, Lixia Zhao*, Liang-Hong Guo*, Hui Zhang, Online Detection of Reactive Oxygen Species in UV-irradiated Nano-TiO2 Suspensions by Continuous Flow Chemiluminescence, Anal. Chem., 2014, 86(21), 10533-10539
13.Lixia Zhao*, Fanglan Geng, Fan Di, Liang-Hong Guo*, Bin Wan, Yu Yang, Hui Zhang, Guozhu Sun, Polyamine-functionalized carbon nanodots:a novel chemiluminescence probe for selective detection of iron (III) ions, RSC Advances, 2014, 4(86), 45768-45771.
14.Lixia Zhao*, Fan Di, Dabin Wang, Liang-Hong Guo*, Yu Yang, Bin wan, Hui Zhang, Chemiluminescence of carbon dots under strong alkaline solutions: A novel insight into carbon dots optical properties, Nanoscale, 2013, 5(7), 2655-2658.
15.Yu. Yang, Lixia Zhao* Sensitive fluorescent sensing for DNA assay, TrAC Trends in Analytical Chemistry, 2010, 29, 980-1003.
16.Zhiyong Li, Qianyun. Zhang, Lixia Zhao,*, Zhenjia Li, Guomao Hu, Jin-Ming Lin, Shan Wang, Micro-plate magnetic chemiluminescence immunoassay and its applications in carcinoembryonic antigen analysis, Science China Chemistry B, 2010, 53,812-819.
17.Lixia Zhao,* Li Sun, Xiaogang Chu “Chemiluminescence immunoassay” TrAC Trends in Analytical Chemistry, 2009,28,404-415.
18.Qin-Zhong Feng, Lixia Zhao,* Wei Yan, Jin-Ming Lin, Zhi-Xia Zheng, “Molecularly imprinted solid-phase extraction combined with high performance liquid chromatography for analysis of phenolic compounds from environmental water samples” Journal of Hazardous Materials, 2009, 167, 282-288.
19.Tianhe Jiang, Lixia Zhao,* Baolin Chu, Qinzhong Feng, Wei Yan, Jin-Ming Lin “Molecularly imprinted solid-phase extraction for the selective determination of 17 -estradiol in fishery samples with high performance liquid chromatography”, Talanta, 2009, 78, 442-447.
20.Bo-Tao Zhang, Lixia Zhao,* Jin-Ming Lin “Determination of folic acid by chemiluminescence based on peroxomonosulfate-cobalt(II) system” Talanta, 2008, 74, 1154-1159.
21.Yong Ma, Bo-Tao Zhang, Lixia Zhao,* Guangsheng Guo, Jin-Ming Lin Determination of Rifampicin by peroxomonosulfate-Cobalt(II) chemiluminescence system,Chinese Journal of Chemistry, 2008, 26, 905-910.
22 Qin-Zhong Feng, Lixia Zhao,* Wei Yan, Feng Ji, Yan-Lin Wei, Jin-Ming Lin Molecularly imprinted solid phase extraction and flow injection chemiluminescence for trace analysis of 2,4-dichlorophenol in water sample, Analytical and Bioanalytical Chemistry, 2008, 391, 1073-1079.
23.Qin-Zhong Feng, Lixia Zhao,* Baolin Chu, Wei Yan, Jin-Ming Lin,Synthesis and binding site characteristics of 2,4,6-trichlorophenol-imprinted polymers, Analytical and Bioanalytical Chemistry, 2008, 392, 1419-1429.
24.Lixia Zhao, Zhenjia Li, Xitang Ying, Jin-Ming Lin,Development of a highly sensitive, second antibody format chemiluminescence enzyme immunoassay for the determination of 17β-estradiol in wastewater,Anal. Chim. Acta,2006, 558(1-2), 290-295.
25.Lixia Zhao, Jin-Ming Lin, Zhenjia Li, Comparison and development of two different solid phase chemiluminescence ELISA for the determination of albumin in urine. Anal. Chim Acta 2005, 541(1-2), 199-207.
26.Lixia Zhao, Jin-Ming Lin, Development of a micro-plate magnetic chemiluminescence enzyme immunoassay (MMCLEIA) for rapid- and high-throughput analysis of 17β-estradiol in water samples, Journal of Biotechnology, 2005, 118(2), 177-186.
27.Lixia Zhao, Baoxin Li, Zhujun Zhang, Jin-Ming Lin, Chemiluminescent flow-through sensor for automated dissolution testing of analgin tablets using manganese dioxide as oxidate, Sensors and Actuators B: Chemical, 2004, 97(2-3): 266-271.
28.王丹,赵利霞*,张辉,郭良宏, 二氧化钛光催化产生超氧自由基的形态分布研究, 分析化学,2017, 45, 1882-1887.
29.马海艳,赵利霞*,张辉,郭良宏,H2O2调控TiO2体系中活性氧物种的产生及其五氯酚降解过程,2018,接受。

编著:

30.赵利霞,张小乐,蔡亚歧,《环境纳米科学与技术》第5章节“纳米技术在环境分析中的应用”。2015, 科学出版社,北京
31.Jin-Ming Lin, Lixia Zhao “Chemiluminescence Chemical Sensing: Fundamentals of Operation and Application for Water Pollutants Control” In “Chemical Sensors: Electrochemical and optical sensors”. 2011, pp.477-495, Momentum Press
32.林金明,赵利霞,王栩 编著 “化学发光免疫分析”,化学工业出版社,2008,北京.
33.林金明,宋冠群,赵利霞 编著 “环境、健康与负氧离子”,化学工业出版社,2008,北京.

中国发明专利

(1)赵利霞, 马海艳,郭良宏,一种五氯酚降解中间体的实时在线动态检测系统,发明专利:201710275290.4
(2)赵利霞,王大彬,郭良宏,光催化反应产生超氧阴离子自由基的实时动态检测系统,中国发明专利,发明专利授权号:ZL 201410158002.3
(3)赵利霞,王大彬,郭良宏,光催化反应产生羟基自由基的实时动态检测系统,中国发明专利,发明专利授权号:ZL 201410157985.9
(4)赵利霞,张付祥,刘振宇,郭良宏 一种微孔板式洗涤—免疫磁性分离全自动一体机,发明专利授权号:ZL 201010199298.5 
(5)郭良宏,黄荣富,赵利霞 “导电微粒子介导电化学发光信号的免疫检测方法” 发明专利授权号:201010591492.0
(6)林金明,曾湖烈,赵利霞,王栩 “纳米金属手性识别固定相、手性分离色谱仪及制备方法” 发明专利授权号: ZL200510126212.5,
(7)林金明,赵利霞,屈锋,一种磁免疫分析分离用的磁性分离器,中国发明专利授权号:ZL 03138349.1.
(8)林金明,赵利霞,屈锋,适用于空板式磁性免疫分析分离技术的磁性分离装置,中国实用新型专利号:ZL 03 2 65041.8.


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