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Professor

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Name	DU Yuguo	Title	N/A
Highest Education	Ph.D	Office	18 Shuangqing Road, Haidian District, Beijing, China
Phone	010-62849126	Zip Code	100085
Fax	010-62923563	Email	duyuguo@rcees.ac.cn

Education and Appointments：

1987.07 Bachelor’s degree, Tsinghua University
1995.06 Ph.D, Research Center for Environmental Sciences, Chinese Academy of Sciences
1995.12-1998.06 Post-doctoral research fellow, College of Pharmacy, The University of Iowa.
2001.01-07 and 2004.06-09 Senior visiting scholar, The University of Iowa, Wayne State University, RPI and Ohio State University.
2001.11- Professor, State Key Laboratory for Environmental Chemistry and Ecotoxicology, Research Center for Environmental Sciences, Chinese Academy of Sciences.
2007.12- Professor, University of Chinese Academy of Sciences.

Research Interest：

Carbohydrate-based design and synthesis of bioactive compounds

Public Services：

Syndic of Chinese Bio-Engineering Society,

Committee member of sugar engineering division, Chinese Bio-Engineering Society,

Committee member of glycoconjugate division, Chinese Biochemistry and Molecular Biology Society,

Board member of <Chinese Science Bulletin>

Board member of <Environmental Chemistry>

Board member of <Open Glycoscience>

Editorial Board Member, Review Editor of <Frontiers in Chemistry>.

Honors：

1996, Presidential Award of Chinese Academy of Sciences, Beijing.
2002, Outstanding Young Scientist Award from Chinese Environmental Science Association.
2006, Outstanding Professor from Graduate University of Chinese Academy of Sciences.
2013, Outstanding Achievement Award from Chinese Academy of Sciences.

Selected Publications：

1.Juan Ma, Peng He, Chuanfang Zhao, Q Ren, Z Dong, J Qiu, Y Jing, Sijin Liu*, Yuguo Du*, A Designed α-GalCer Analog Promotes Considerable Th1 Cytokine Response by Activating the CD1d-iNKT Axis and CD11b-Positive Monocytes/Macrophages, Advanced Science 2020, 2000609.

2.Peng He, Chuanfang Zhao, Jiao Lu, Yang Zhang, Min Fang, and Yuguo Du*, Synthesis of 5-Thio-α-GalCer Analogues with Fluorinated Acyl Chain on Lipid Residue and Their Biological Evaluation. ACS Med Chem lett. 2019, 2, 221-225.

3.Wen Q, Xie X, Zhao C, Ren Q, Zhang X, Wei D, Brice Emanuelli, Yuguo Du*. The brominated flame retardant PBDE 99 promotes adipogenesis via regulating mitotic clonal expansion and PPARgamma expression. Sci Total Environ 2019, 670, 67-77.

4.Jialin Geng, Qidong Ren, Caizhu Chang, Xinni Xie, Jun Liu, Yuguo Du*. Synthesis and biological activities of petrosiols B and D, RSC Advances, 2019, 9, 10253-10263.

5.Xuefeng Sun, Dongbin Wei*, Wei Liu, Jialin Geng, Jun Liu, Yuguo Du*, Formation of novel disinfection by-products chlorinated benzoquinone, phenyl benzoquinones and polycyclic aromatic hydrocarbons during chlorination treatment on UV filter 2,4-dihydroxy benzophenone in swimming pool water, J Hazard Mater 2019, 367, 725-733.

6.Yi Liu, Peng He, Yang Zhang, Xiangyu Zhang, Jun Liu, Yuguo Du*, One-Pot Enantiomeric Synthesis of Thiazole-Containing Amino Acids: Total Synthesis of Venturamides A and B, J Org Chem 2018, 83, 3897-3905.

7.Yong Wang, Miao Liu, Lei Liu, Jian-Hui Xia, Yuguo Du,* Jian-Song Sun*, The Structural Revision and Total Synthesis of Carambolaflavone A, J Org Chem 2018, 83, 4111-4118.

8.Junfei Qiao, Chuanfang Zhao, Jun Liu, Yuguo Du*, Design and synthesis of selenazole-substituted ritonavir analogs, Bioorg & Med Chem Lett 2018, 28, 2379-2381.

9.Jing Liu, Linlin Wang, Yuguo Du, Sijin Liu, An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress. Advanced Science 2017, 4, 1700089.

10.Jingjing Bi, Jing Wang, Kai Zhou, Yuancheng Wang, Min Fang, and Yuguo Du, Synthesis and Biological Activities of 5-Thio-a-GalCers, ACS Med Chem Lett, 2015, 6, 476-480.

11.Xue Sun, Yi Liu, Jun Liu, Guofeng Gu, Yuguo Du, Synthesis and structural reconfirmation of bacillamide B, Org. Biomol. Chem. 2015, 13, 4271-4277.

12.Yangguang Gao, Qiuli Shan, Jun Liu, Linlin Wang, Yuguo Du, The first convergent total synthesis of penarolide sulfate A2, a novel a-glucosidase inhibitor, Org. Biomol. Chem. 2014, 12, 2071-2079.

13.Xing Ma, Jing Wang, Qiuli Shan, Zhuowei Tan, Guohua Wei, Dongbin Wei, Yuguo Du, Org. Lett. 2012, 14(3), 820-823.

14.Jun Liu, Yi Liu, Xing Zhang, Chaoli Zhang, Yuguo Du, Total Synthesis of (-)-Orthodiffenes A and C, J. Org. Chem. 2012, 77, 9718?9723.

15.Yi Liu, Jun Liu, Yuguo Du, One-Pot Synthesis of 2,4-Disubstituted Thiazoline from β-Azido Disulfide and Carboxylic Acid, J. Org. Chem. 2012, 77, 7108-7113.

Supported Projects：

1) Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No.
XDB14040201),
2) 973 Projects from MOSTC (project 2015CB931903),
3) Projects from NNSFC (projects 21672255 and 21621064),
4) Technology Service Project for COFCO, China.